Read on to learn about the side effects of metoprolol, including common, severe, and long-term side effects, and how to manage them. Metoprolol succinate extended-release tablets are indicated for the treatment of hypertension, to lower blood pressure. Lowering blood pressure lowers the risk of fatal and non-fatal cardiovascular events, primarily strokes and myocardial infarctions. These benefits have been seen in controlled trials of antihypertensive drugs from a wide variety of pharmacologic classes including metoprolol. Toprol XL (Metoprolol Succinate) may treat, side effects, dosage, drug interactions, warnings, patient labeling, reviews, and related medications including drug comparison and health resources. Metoprolol may worsen the symptoms of heart failure in some patients. Check with your doctor right away if you are having chest pain or discomfort, dilated neck veins, extreme fatigue, irregular breathing or heartbeat, swelling of the face, fingers, feet, or lower legs, trouble breathing, or weight gain. Metoprolol succinate is a white crystalline powder with a molecular weight of 652.8. It is freely soluble in water; soluble in methanol; sparingly soluble in ethanol; slightly soluble in dichloromethane and 2-propanol; practically insoluble in ethyl-acetate, acetone, diethylether and heptane. Inactive ingredients: silicon dioxide, cellulose compounds, sodium stearyl fumarate, polyethylene. Find patient medical information for Metoprolol (Lopressor, Toprol XL, others) on WebMD including its uses, side effects and safety, interactions, pictures, warnings, and user ratings The FDA recalled over 112,000 bottles of metoprolol succinate due to possible contamination, urging patients to check lot numbers right away. Metoprolol Tablets Metoprolol (Lopressor®) is a medication that lowers your blood pressure and heart rate, making it easier for your heart to pump blood to the rest of your body. It treats high blood pressure. It also prevents chest pain or further damage after a heart attack. It’s a type of beta-blocker. Metoprolol is used to treat angina (chest pain) and hypertension (high blood pressure). Learn about side effects, interactions and indications. Metoprolol belongs to a class of drugs known as beta blockers. It works by blocking the action of certain natural substances in your body, such as epinephrine, on the heart and blood vessels.